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Molecular characterization confirms the presence of a divergent strain of canine coronavirus (UWSMN-1) in Australia.

ABSTRACT: Canine coronavirus (CCV) UWSMN-1 was originally identified from an outbreak of fatal gastroenteritis in breeding colonies. In this report, we examined whether UWSMN-1 represents a novel divergent strain or is the result of recombination events between canine and feline coronavirus strains. Sequencing of various regions of the spike and polymerase genes confirms that UWSMN-1 is widely divergent from other CCV and feline coronavirus strains. These data raise the possibility that this strain is the first member of a novel third subtype of CCV.

SUBMITTER: Naylor MJ

PROVIDER: S-EPMC130832 | biostudies-literature | 2002 Sep

REPOSITORIES: biostudies-literature

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Molecular characterization confirms the presence of a divergent strain of canine coronavirus (UWSMN-1) in Australia.

Naylor Matthew J MJ Walia Charanjiv S CS McOrist Steven S Lehrbach Philip R PR Deane Elizabeth M EM Harrison Gavan A GA

Journal of clinical microbiology 20020901 9

Canine coronavirus (CCV) UWSMN-1 was originally identified from an outbreak of fatal gastroenteritis in breeding colonies. In this report, we examined whether UWSMN-1 represents a novel divergent strain or is the result of recombination events between canine and feline coronavirus strains. Sequencing of various regions of the spike and polymerase genes confirms that UWSMN-1 is widely divergent from other CCV and feline coronavirus strains. These data raise the possibility that this strain is the ...[more]

PMID: 12202609

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