Mitochondrial transfer between cells can rescue aerobic respiration.
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ABSTRACT:
SUBMITTER: Spees JL
PROVIDER: S-EPMC1345715 | biostudies-literature | 2006 Jan
REPOSITORIES: biostudies-literature
Publications
Mitochondrial transfer between cells can rescue aerobic respiration.
Spees Jeffrey L JL Olson Scott D SD Whitney Mandolin J MJ Prockop Darwin J DJ
Proceedings of the National Academy of Sciences of the United States of America 20060123 5
Current theory indicates that mitochondria were obtained 1.5 billion years ago from an ancient prokaryote. The mitochondria provided the capacity for aerobic respiration, the creation of the eukaryotic cell, and eventually complex multicellular organisms. Recent reports have found that mitochondria play essential roles in aging and determining lifespan. A variety of heritable and acquired diseases are linked to mitochondrial dysfunction. We report here that mitochondria are more dynamic than pre ...[more]
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