Ontology highlight
ABSTRACT:
SUBMITTER: Ueda K
PROVIDER: S-EPMC134859 | biostudies-literature | 2002 Mar
REPOSITORIES: biostudies-literature
Ueda Kenji K Oinuma Ken-Ichi K Ikeda Go G Hosono Kuniaki K Ohnishi Yasuo Y Horinouchi Sueharu S Beppu Teruhiko T
Journal of bacteriology 20020301 5
The amf gene cluster was previously identified as a regulator for the onset of aerial-mycelium formation in Streptomyces griseus. The nucleotide sequences of amf and its counterparts in other species revealed a conserved gene organization consisting of five open reading frames. A nonsense mutation in amfS, encoding a 43-amino-acid peptide, caused significant blocking of aerial-mycelium formation and streptomycin production, suggesting its role as a regulatory molecule. Extracellular-complementat ...[more]