Ontology highlight
ABSTRACT:
SUBMITTER: Enjalbert B
PROVIDER: S-EPMC1356608 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Enjalbert Brice B Smith Deborah A DA Cornell Michael J MJ Alam Intikhab I Nicholls Susan S Brown Alistair J P AJ Quinn Janet J
Molecular biology of the cell 20051207 2
The resistance of Candida albicans to many stresses is dependent on the stress-activated protein kinase (SAPK) Hog1. Hence we have explored the role of Hog1 in the regulation of transcriptional responses to stress. DNA microarrays were used to characterize the global transcriptional responses of HOG1 and hog1 cells to three stress conditions that activate the Hog1 SAPK: osmotic stress, oxidative stress, and heavy metal stress. This revealed both stress-specific transcriptional responses and a co ...[more]