Ontology highlight
ABSTRACT:
SUBMITTER: Harano Y
PROVIDER: S-EPMC1366771 | biostudies-literature | 2005 Oct
REPOSITORIES: biostudies-literature
Biophysical journal 20050729 4
We show that even in the complete absence of potential energies among the atoms in a protein-aqueous solution system, there is a physical factor that favors the folded state of the protein. It is a gain in the translational entropy (TE) of water originating from the translational movement of water molecules. An elaborate statistical-mechanical theory is employed to analyze the TE of water in which a protein or peptide with a prescribed conformation is immersed. It is shown that if the number of ...[more]