DNA sequences shaped by selection for stability.
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ABSTRACT:
SUBMITTER: Ackermann M
PROVIDER: S-EPMC1378130 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Publications
DNA sequences shaped by selection for stability.
PLoS genetics 20060224 2
The sequence of a stretch of nucleotides affects its propensity for errors during replication and expression. Are proteins encoded by stable or unstable nucleotide sequences? If selection for variability is prevalent, one could expect an excess of unstable sequences. Alternatively, if selection against targets for errors were substantial, an excess of stable sequences would be expected. We screened the genome sequences of different organisms for an important determinant of stability, the presenc ...[more]
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