Natural transformation-mediated transfer of erythromycin resistance in Campylobacter coli strains from turkeys and swine.

ABSTRACT: Erythromycin resistance in Campylobacter coli from meat animals is frequently encountered and could represent a substantial barrier to antibiotic treatment of human infections. Erythromycin resistance in this organism has been associated with a point mutation (A2075G) in the 23S rRNA gene. However, the mechanisms responsible for possible dissemination of erythromycin resistance in C. coli remain poorly understood. In this study, we investigated transformation-mediated acquisition of erythromycin resistance by genotypically diverse C. coli strains from turkeys and swine, with total genomic DNA from erythromycin-resistant C. coli of either turkey or swine origin used as a donor. Overall, transformation to erythromycin resistance was significantly more frequent in C. coli strains from turkeys

SUBMITTER: Kim JS 

PROVIDER: S-EPMC1392931 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature