Ontology highlight
ABSTRACT:
SUBMITTER: Aggarwal VK
PROVIDER: S-EPMC1399452 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20050826 1
The degree of reagent and substrate control in the reaction of chiral sulfur ylides with chiral aldehydes has been investigated. Specifically, the reactions of the two enantiomers of the chiral benzyl sulfonium salt 1 with glyceraldehyde acetonide were studied in detail. Of the two new stereogenic centers created, it was found that the C1 stereochemistry was largely controlled by the reagent, whereas control at the C2 center was dependent on the aldehyde used. In one case, the trans isomer was p ...[more]