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Identification and characterization of the gerH operon of Bacillus anthracis endospores: a differential role for purine nucleosides in germination.


ABSTRACT: We identified a tri-cistronic operon, gerH, in Bacillus anthracis that is important for endospore germination triggered by two distinct germination response pathways termed inosine-His and purine-Ala. Together, the two pathways allow B. anthracis endospores a broader recognition of purines and amino acids that may be important for host-mediated germination.

SUBMITTER: Weiner MA 

PROVIDER: S-EPMC142867 | biostudies-literature | 2003 Feb

REPOSITORIES: biostudies-literature

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Identification and characterization of the gerH operon of Bacillus anthracis endospores: a differential role for purine nucleosides in germination.

Weiner Matthew A MA   Read Timothy D TD   Hanna Philip C PC  

Journal of bacteriology 20030201 4


We identified a tri-cistronic operon, gerH, in Bacillus anthracis that is important for endospore germination triggered by two distinct germination response pathways termed inosine-His and purine-Ala. Together, the two pathways allow B. anthracis endospores a broader recognition of purines and amino acids that may be important for host-mediated germination. ...[more]

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