Ontology highlight
ABSTRACT:
SUBMITTER: Hall BG
PROVIDER: S-EPMC1459372 | biostudies-literature | 2006 Apr
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20060327 14
There are a variety of reasons to reconstruct the sequences of ancient proteins, but whatever the reason, the value of the reconstructed protein depends on the accuracy with which the ancient sequence is inferred. This study uses sequences simulated by a sequence-evolution simulation program that compares parsimony, maximum likelihood, and the Bayesian methods of inferring ancestral sequences and concludes that the Bayesian method, as implemented by MRBAYES 3.11, is preferred. Estimated ancestra ...[more]