Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC1464845 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Wang Shuying S Hu Yaoxiong Y Overgaard Michael T MT Karginov Fedor V FV Uhlenbeck Olke C OC McKay David B DB
RNA (New York, N.Y.) 20060412 6
The YxiN protein of Bacillus subtilis is a member of the DbpA subfamily of prokaryotic DEAD-box RNA helicases. Like DbpA, it binds with high affinity and specificity to segments of 23S ribosomal RNA as short as 32 nucleotides (nt) that include hairpin 92. Several experiments have shown that the 76-residue carboxy-terminal domain of YxiN is responsible for the high-affinity RNA binding. The domain has been crystallized and its structure has been solved to 1.7 Angstroms resolution. The structure r ...[more]