Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC2134858 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Wang Shuying S Overgaard Michael T MT Hu YaoXiong Y McKay David B DB
Biophysical journal 20071019 1
The Bacillus subtilis YxiN protein is a modular three-domain RNA helicase of the DEx(D/H)-box protein family. The first two domains form the highly conserved helicase core, and the third domain confers RNA target binding specificity. Small angle x-ray scattering on YxiN and two-domain fragments thereof shows that the protein has a distended structure in solution, in contrast to helicases involved in replication processes. These data are consistent with a chaperone activity in which the carboxy-t ...[more]