Ontology highlight
ABSTRACT:
SUBMITTER: Perry GH
PROVIDER: S-EPMC1472420 | biostudies-literature | 2006 May
REPOSITORIES: biostudies-literature
Perry George H GH Tchinda Joelle J McGrath Sean D SD Zhang Junjun J Picker Simon R SR Cáceres Angela M AM Iafrate A John AJ Tyler-Smith Chris C Scherer Stephen W SW Eichler Evan E EE Stone Anne C AC Lee Charles C
Proceedings of the National Academy of Sciences of the United States of America 20060515 21
Copy number variation is surprisingly common among humans and can be involved in phenotypic diversity and variable susceptibility to complex diseases, but little is known of the extent of copy number variation in nonhuman primates. We have used two array-based comparative genomic hybridization platforms to identify a total of 355 copy number variants (CNVs) in the genomes of 20 wild-born chimpanzees (Pan troglodytes) and have compared the identified chimpanzee CNVs to known human CNVs from previ ...[more]