Ontology highlight
ABSTRACT:
SUBMITTER: Meng Y
PROVIDER: S-EPMC1474030 | biostudies-literature | 2006 May
REPOSITORIES: biostudies-literature
Meng Yan Y Baldwin Clinton T CT Bowirrat Abdalla A Waraska Kristin K Inzelberg Rivka R Friedland Robert P RP Farrer Lindsay A LA
American journal of human genetics 20060316 5
Several lines of evidence support for a role of angiotensin converting enzyme (ACE) in Alzheimer disease (AD). Most genetic studies have focused on an Alu insertion/deletion (I/D) polymorphism in the ACE gene (DCP1) and have yielded conflicting results. We evaluated the association between 15 single-nucleotide polymorphisms (SNPs) in DCP1, including the I/D variant, and AD in a sample of 92 patients with AD and 166 nondemented controls from an inbred Israeli Arab community. Although there was no ...[more]