Ontology highlight
ABSTRACT:
SUBMITTER: Gaffney PM
PROVIDER: S-EPMC1474034 | biostudies-literature | 2006 May
REPOSITORIES: biostudies-literature
Gaffney Patrick M PM Langefeld Carl D CD Graham Robert R RR Ortmann Ward A WA Williams Adrienne H AH Rodine Peter R PR Moser Kathy L KL Behrens Timothy W TW
American journal of human genetics 20060316 5
The presence of systemic lupus erythematosus (SLE) susceptibility genes on chromosome 20 is suggested by the observation of genetic linkage in several independent SLE family collections. To further localize the genetic effects, we typed 59 microsatellites in the two best regions, as defined by genome screens. Genotypes were analyzed for statistical linkage and/or association with SLE, by use of a combination of nonparametric linkage methods, family-based tests of association (transmission/disequ ...[more]