Ontology highlight
ABSTRACT:
SUBMITTER: Moffitt JR
PROVIDER: S-EPMC1482556 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20060602 24
The drive toward more sensitive single-molecule manipulation techniques has led to the recent development of optical tweezers capable of resolving the motions of biological systems at the subnanometer level, approaching the fundamental limit set by Brownian fluctuations. One successful approach has been the dual-trap optical tweezers, in which the system of study is held at both ends by microspheres in two separate optical traps. We present here a theoretical description of the Brownian limit on ...[more]