Ontology highlight
ABSTRACT:
SUBMITTER: Wang C
PROVIDER: S-EPMC1483041 | biostudies-literature | 2006 Jul
REPOSITORIES: biostudies-literature
Wang Chen C Xia Caihong C Bian Wei W Liu Li L Lin Wei W Chen Ye-Guang YG Ang Siew-Lan SL Jing Naihe N
Molecular biology of the cell 20060426 7
FGF8, a member of the fibroblast growth factor (FGF) family, has been shown to play important roles in different developing systems. Mouse embryonic carcinoma P19 cells could be induced by retinoic acid (RA) to differentiate into neuroectodermal cell lineages, and this process is cell aggregation dependent. In this report, we show that FGF8 expression is transiently up-regulated upon P19 cell aggregation, and the aggregation-dependent FGF8 elevation is pluripotent stem cell related. Overexpressi ...[more]