Ontology highlight
ABSTRACT:
SUBMITTER: Piljic A
PROVIDER: S-EPMC1483058 | biostudies-literature | 2006 Jul
REPOSITORIES: biostudies-literature
Piljic Alen A Schultz Carsten C
Molecular biology of the cell 20060510 7
Annexins are Ca2+-regulated phospholipid-binding proteins whose function is only partially understood. Annexin A4 is a member of this family that is believed to be involved in exocytosis and regulation of epithelial Cl- secretion. In this work, fluorescent protein fusions of annexin A4 were used to investigate Ca2+-induced annexin A4 translocation and self-association on membrane surfaces in living cells. We designed a novel, genetically encoded, FRET sensor (CYNEX4) that allowed for easy quanti ...[more]