Cochlin and glaucoma: a mini-review.
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ABSTRACT:
SUBMITTER: Bhattacharya SK
PROVIDER: S-EPMC1483214 | biostudies-literature | 2005 Sep-Oct
REPOSITORIES: biostudies-literature
Publications
Cochlin and glaucoma: a mini-review.
Bhattacharya Sanjoy K SK Peachey Neal S NS Crabb John W JW
Visual neuroscience 20050901 5
Primary open angle glaucoma (POAG) is a leading cause of late onset, progressive, irreversible blindness and, although its etiology is poorly understood, elevated intraocular pressure (IOP) often appears to be a contributory factor. Proteomic and Western analyses of trabecular meshwork (TM) from patients with POAG and age-matched controls originally implicated cochlin as possibly contributing to glaucoma pathogenesis. Cochlin deposits were subsequently detected in glaucomatous but not in control ...[more]
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