Immunology of Osteoporosis: A Mini-Review.
Ontology highlight
ABSTRACT:
SUBMITTER: Pietschmann P
PROVIDER: S-EPMC4821368 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Publications
Immunology of Osteoporosis: A Mini-Review.
Pietschmann Peter P Mechtcheriakova Diana D Meshcheryakova Anastasia A Föger-Samwald Ursula U Ellinger Isabella I
Gerontology 20150617 2
Osteoporosis is a major cause of fractures and associated morbidity in the aged population. The pathogenesis of osteoporosis is multifactorial; whereas traditional pathophysiological concepts emphasize endocrine mechanisms, it has been recognized that also components of the immune system have a significant impact on bone. Since 2000, when the term 'osteoimmunology' was coined, novel insights into the role of inflammatory cytokines by influencing the fine-tuned balance between bone resorption and ...[more]
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