Ontology highlight
ABSTRACT:
SUBMITTER: Deocaris CC
PROVIDER: S-EPMC1484513 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Deocaris Custer C CC Kaul Sunil C SC Wadhwa Renu R
Cell stress & chaperones 20060101 2
The heat shock chaperones mortalin/mitochondrial heat shock protein 70 (mtHsp70) and Hsp60 are found in multiple subcellular sites and function in the folding and intracellular trafficking of many proteins. The chaperoning activity of these 2 proteins involves different structural and functional mechanisms. In spite of providing an excellent model for an evolutionarily conserved molecular "brotherhood", their individual functions, although overlapping, are nonredundant. As they travel to various ...[more]