Unknown

Dataset Information

0

Lamivudine resistance of hepatitis B virus masked by coemergence of mutations in probe region of the COBAS AMPLICOR assay.

ABSTRACT: The COBAS AMPLICOR hepatitis B virus assay targets a conserved region of the genome and is widely used to monitor treatment of hepatitis B in order to identify emerging resistance. However, the assay failed to recognize increasing viremia levels when YMDD mutations were paralleled by mutations in the segment targeted by the COBAS AMPLICOR probe.

SUBMITTER: Lindh M 

PROVIDER: S-EPMC1489515 | biostudies-literature | 2006 Jul

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Lamivudine resistance of hepatitis B virus masked by coemergence of mutations in probe region of the COBAS AMPLICOR assay.

Lindh Magnus M   Hannoun Charles C   Malmström Sebastian S   Lindberg Johan J   Norkrans Gunnar G  

Journal of clinical microbiology 20060701 7

The COBAS AMPLICOR hepatitis B virus assay targets a conserved region of the genome and is widely used to monitor treatment of hepatitis B in order to identify emerging resistance. However, the assay failed to recognize increasing viremia levels when YMDD mutations were paralleled by mutations in the segment targeted by the COBAS AMPLICOR probe. ...[more]

Similar Datasets

Unknown Evolution of primary and compensatory lamivudine resistance mutations in chronic hepatitis B virus-infected patients during long-term lamivudine treatment, assessed by a line probe assay.
| S-EPMC2168556 | biostudies-literature
Unknown Neisseria species identification assay for the confirmation of Neisseria gonorrhoeae-positive results of the COBAS Amplicor PCR.
| S-EPMC1865884 | biostudies-literature
Unknown Validation of roche COBAS Amplicor assay for detection of Chlamydia trachomatis in rectal and pharyngeal specimens by an omp1 PCR assay.
| S-EPMC321736 | biostudies-literature
Unknown Comparison of a duplex quantitative real-time PCR assay and the COBAS Amplicor CMV Monitor test for detection of cytomegalovirus.
| S-EPMC404600 | biostudies-literature
Unknown Second-generation Cobas AmpliPrep/Cobas TaqMan HCV quantitative test for viral load monitoring: a novel dual-probe assay design.
| S-EPMC3553902 | biostudies-other
Unknown Development and validation of an oligonucleotide ligation assay to detect lamivudine resistance in hepatitis B virus.
| S-EPMC5074383 | biostudies-literature
Unknown Dynamics of hepatitis B virus resistance to lamivudine.
| S-EPMC1346832 | biostudies-literature
Unknown A Highly Prevalent Polymorphism in the Core Region Impairs Quantification of Hepatitis B Virus (HBV) by the cobas TaqMan HBV Assay.
| S-EPMC7448625 | biostudies-literature
Unknown Detection and identification of Mycobacterium spp. in clinical specimens by combining the Roche Cobas Amplicor Mycobacterium tuberculosis assay with Mycobacterium genus detection and nucleic acid sequencing.
| S-EPMC3020847 | biostudies-literature
Unknown Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil.
| S-EPMC2245951 | biostudies-literature