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Escherichia coli with a self-transferable, multiresistant plasmid coding for metallo-beta-lactamase VIM-1.


ABSTRACT: An Escherichia coli strain exhibiting decreased susceptibility to carbapenems was isolated from a hospitalized patient in Greece. The strain carried a self-transferable plasmid coding for metallo-beta-lactamase VIM-1. bla(VIM-1), along with aacA7, dhfrI, and aadA, was included as a gene cassette in a novel class 1 integron. A Citrobacter freundii ampC-derived gene, not associated with the integron, was also located in the same plasmid.

SUBMITTER: Miriagou V 

PROVIDER: S-EPMC149029 | biostudies-literature | 2003 Jan

REPOSITORIES: biostudies-literature

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Escherichia coli with a self-transferable, multiresistant plasmid coding for metallo-beta-lactamase VIM-1.

Miriagou Vivi V   Tzelepi Eva E   Gianneli Dimitra D   Tzouvelekis Leonidas S LS  

Antimicrobial agents and chemotherapy 20030101 1


An Escherichia coli strain exhibiting decreased susceptibility to carbapenems was isolated from a hospitalized patient in Greece. The strain carried a self-transferable plasmid coding for metallo-beta-lactamase VIM-1. bla(VIM-1), along with aacA7, dhfrI, and aadA, was included as a gene cassette in a novel class 1 integron. A Citrobacter freundii ampC-derived gene, not associated with the integron, was also located in the same plasmid. ...[more]

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