Ontology highlight
ABSTRACT:
SUBMITTER: Boni IV
PROVIDER: S-EPMC149162 | biostudies-literature | 2001 Aug
REPOSITORIES: biostudies-literature
Boni I V IV Artamonova V S VS Tzareva N V NV Dreyfus M M
The EMBO journal 20010801 15
Translation initiation region (TIR) of the rpsA mRNA encoding ribosomal protein S1 is one of the most efficient in Escherichia coli despite the absence of a canonical Shine-Dalgarno-element. Its high efficiency is under strong negative autogenous control, a puzzling phenomenon as S1 has no strict sequence specificity. To define sequence and structural elements responsible for translational efficiency and autoregulation of the rpsA mRNA, a series of rpsA'-'lacZ chromosomal fusions bearing various ...[more]