Clonal dissemination of Yersinia enterocolitica strains with various susceptibilities to nalidixic acid.
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ABSTRACT:
SUBMITTER: Sanchez-Cespedes J
PROVIDER: S-EPMC153901 | biostudies-literature | 2003 Apr
REPOSITORIES: biostudies-literature
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Clonal dissemination of Yersinia enterocolitica strains with various susceptibilities to nalidixic acid.
Sánchez-Céspedes Javier J Navia Margarita M MM Martínez Rocío R Orden Beatriz B Millán Rosario R Ruiz Joaquín J Vila Jordi J
Journal of clinical microbiology 20030401 4
Ten epidemiologically related Yersinia enterocolitica clinical isolates were studied. Six isolates were nalidixic acid resistant (MIC > 512 microg/ml), with mutations in the quinolone resistance-determining region (QRDR) of the gyrA gene, suggesting clonal dissemination of a nalidixic acid-susceptible Y. enterocolitica strain which has acquired different mutations generating resistance to nalidixic acid. ...[more]
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