Ontology highlight
ABSTRACT:
SUBMITTER: Simpson KW
PROVIDER: S-EPMC1539603 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Simpson Kenneth W KW Dogan Belgin B Rishniw Mark M Goldstein Richard E RE Klaessig Suzanne S McDonough Patrick L PL German Alex J AJ Yates Robin M RM Russell David G DG Johnson Susan E SE Berg Douglas E DE Harel Josee J Bruant Guillaume G McDonough Sean P SP Schukken Ynte H YH
Infection and immunity 20060801 8
The mucosa-associated microflora is increasingly considered to play a pivotal role in the pathogenesis of inflammatory bowel disease. This study explored the possibility that an abnormal mucosal flora is involved in the etiopathogenesis of granulomatous colitis of Boxer dogs (GCB). Colonic biopsy samples from affected dogs (n = 13) and controls (n = 38) were examined by fluorescent in situ hybridization (FISH) with a eubacterial 16S rRNA probe. Culture, 16S ribosomal DNA sequencing, and histoche ...[more]