Ontology highlight
ABSTRACT:
SUBMITTER: Teare MD
PROVIDER: S-EPMC1559538 | biostudies-literature | 2006 Sep
REPOSITORIES: biostudies-literature
Teare M D MD Heighway J J Santibáñez Koref M F MF
American journal of human genetics 20060630 3
A significant proportion of the variation between individuals in gene expression levels is genetic, and it is likely that these differences correlate with phenotypic differences or with risk of disease. Cis-acting polymorphisms are important in determining interindividual differences in gene expression that lead to allelic expression imbalance, which is the unequal expression of homologous alleles in individuals heterozygous for such a polymorphism. This expression imbalance can be detected usin ...[more]