Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC156766 | biostudies-literature | 2003 Jun
REPOSITORIES: biostudies-literature
Zhang Ying Y Corver Jeroen J Chipman Paul R PR Zhang Wei W Pletnev Sergei V SV Sedlak Dagmar D Baker Timothy S TS Strauss James H JH Kuhn Richard J RJ Rossmann Michael G MG
The EMBO journal 20030601 11
Structures of prM-containing dengue and yellow fever virus particles were determined to 16 and 25 A resolution, respectively, by cryoelectron microscopy and image reconstruction techniques. The closely similar structures show 60 icosahedrally organized trimeric spikes on the particle surface. Each spike consists of three prM:E heterodimers, where E is an envelope glycoprotein and prM is the precursor to the membrane protein M. The pre-peptide components of the prM proteins in each spike cover th ...[more]