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ABSTRACT:
SUBMITTER: Venkova-Canova T
PROVIDER: S-EPMC1567695 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Venkova-Canova Tatiana T Srivastava Preeti P Chattoraj Dhruba K DK
Proceedings of the National Academy of Sciences of the United States of America 20060727 32
The bacterium Vibrio cholerae has two chromosomes. The origin of replication of chromosome I is similar to that of Escherichia coli. The origin-containing region of chromosome II (oriCII) resembles replicons of plasmids such as P1, except for the presence of an additional gene, rctA [Egan, E. S. & Waldor, M. K. (2003) Cell 114, 521-530]. The oriCII region that includes the initiator gene, rctB, can function as a plasmid in E. coli. Here we show that RctB suffices for the oriCII-based plasmid rep ...[more]