Ontology highlight
ABSTRACT:
SUBMITTER: Noda T
PROVIDER: S-EPMC1579243 | biostudies-literature | 2006 Sep
REPOSITORIES: biostudies-literature
Noda Takeshi T Ebihara Hideki H Muramoto Yukiko Y Fujii Ken K Takada Ayato A Sagara Hiroshi H Kim Jin Hyun JH Kida Hiroshi H Feldmann Heinz H Kawaoka Yoshihiro Y
PLoS pathogens 20060901 9
Ebolavirus is responsible for highly lethal hemorrhagic fever. Like all viruses, it must reproduce its various components and assemble them in cells in order to reproduce infectious virions and perpetuate itself. To generate infectious Ebolavirus, a viral genome-protein complex called the nucleocapsid (NC) must be produced and transported to the cell surface, incorporated into virions, and then released from cells. To further our understanding of the Ebolavirus life cycle, we expressed the vario ...[more]