Ontology highlight
ABSTRACT:
SUBMITTER: Craciun G
PROVIDER: S-EPMC1592242 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Craciun Gheorghe G Tang Yangzhong Y Feinberg Martin M
Proceedings of the National Academy of Sciences of the United States of America 20060530 23
Much attention has been paid recently to bistability and switch-like behavior that might be resident in important biochemical reaction networks. There is, in fact, a great deal of subtlety in the relationship between the structure of a reaction network and its capacity to engender bistability. In common physicochemical settings, large classes of extremely complex networks, taken with mass action kinetics, cannot give rise to bistability no matter what values the rate constants take. On the other ...[more]