Characterising Complex Enzyme Reaction Data.
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ABSTRACT:
SUBMITTER: Donertas HM
PROVIDER: S-EPMC4740462 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Characterising Complex Enzyme Reaction Data.
Dönertaş Handan Melike HM Martínez Cuesta Sergio S Rahman Syed Asad SA Thornton Janet M JM
PloS one 20160203 2
The relationship between enzyme-catalysed reactions and the Enzyme Commission (EC) number, the widely accepted classification scheme used to characterise enzyme activity, is complex and with the rapid increase in our knowledge of the reactions catalysed by enzymes needs revisiting. We present a manual and computational analysis to investigate this complexity and found that almost one-third of all known EC numbers are linked to more than one reaction in the secondary reaction databases (e.g., KEG ...[more]
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