Ontology highlight
ABSTRACT:
SUBMITTER: Liao GC
PROVIDER: S-EPMC16242 | biostudies-literature | 2000 Mar
REPOSITORIES: biostudies-literature
Liao G C GC Rehm E J EJ Rubin G M GM
Proceedings of the National Academy of Sciences of the United States of America 20000301 7
We determined the genomic sequence at the site of insertion in 2,266 unselected P element insertion events. Estimating physical properties of the genomic DNA at these insertion sites-such as base composition, bendability, A-philicity, protein-induced deformability, and B-DNA twist-revealed that they differ significantly from average chromosomal DNA. By examining potential hydrogen bonding sites in the major groove, we identified a 14-bp palindromic pattern centered on the 8-bp target site duplic ...[more]