Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC1630420 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Wang Yiguo Y Du Dan D Fang Longhou L Yang Guang G Zhang Chenyi C Zeng Rong R Ullrich Axel A Lottspeich Friedrich F Chen Zhengjun Z
The EMBO journal 20061019 21
The conserved polarity complex, comprising the partitioning-defective (Par) proteins Par3 and Par6, and the atypical protein kinase C, functions in various cell-polarization events and asymmetric cell divisions. However, little is known about whether and how external stimuli-induced signals may regulate Par3 function in epithelial cell polarity. Here, we found that Par3 was tyrosine phosphorylated through phosphoproteomic profiling of pervanadate-induced phosphotyrosine proteins. We also demonst ...[more]