Ontology highlight
ABSTRACT:
SUBMITTER: Artavanis-Tsakonas K
PROVIDER: S-EPMC1635107 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Artavanis-Tsakonas Katerina K Love J Christopher JC Ploegh Hidde L HL Vyas Jatin M JM
Proceedings of the National Academy of Sciences of the United States of America 20061016 43
The subcellular localization of the cluster of differentiation 63 (CD63) tetraspanin and its interaction with the class II MHC antigen presentation pathway were examined in the context of phagocytosis by live cell imaging, by using monomeric red fluorescent protein-tagged mouse CD63 expressed in primary bone marrow-derived cell cultures. Upon phagocytosis of Cryptococcus neoformans and polystyrene beads, CD63 was recruited selectively to C. neoformans-containing phagosomes in a MyD88-independent ...[more]