Ontology highlight
ABSTRACT:
SUBMITTER: Yu L
PROVIDER: S-EPMC1635385 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Yu Lisa L Peña Castillo Lourdes L Mnaimneh Sanie S Hughes Timothy R TR Brown Grant W GW
Molecular biology of the cell 20060830 11
Mutations impacting specific stages of cell growth and division have provided a foundation for dissecting mechanisms that underlie cell cycle progression. We have undertaken an objective examination of the yeast cell cycle through flow cytometric analysis of DNA content in TetO(7) promoter mutant strains representing 75% of all essential yeast genes. More than 65% of the strains displayed specific alterations in DNA content, suggesting that reduced function of an essential gene in most cases imp ...[more]