Ontology highlight
ABSTRACT:
SUBMITTER: Pineda JR
PROVIDER: S-EPMC1647311 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20060801 1472
This manuscript describes ongoing research on the nature of chemical reactions in enzymes. We will investigate how protein dynamics can couple to chemical reaction in an enzyme. We first investigate in some detail why transition state theory cannot fully describe the dynamics of chemical reactions catalysed by enzymes. We describe quantum theories of chemical reaction in condensed phase including studies of how the symmetry of coupled vibrational modes differentially affects reaction dynamics. W ...[more]