Ontology highlight
ABSTRACT:
SUBMITTER: Lefkir Y
PROVIDER: S-EPMC165081 | biostudies-literature | 2003 May
REPOSITORIES: biostudies-literature
Lefkir Yaya Y de Chassey Benoît B Dubois Annick A Bogdanovic Aleksandra A Brady Rebecca J RJ Destaing Olivier O Bruckert Franz F O'Halloran Theresa J TJ Cosson Pierre P Letourneur François F
Molecular biology of the cell 20030126 5
Adaptor protein complexes (AP) are major components of the cytoplasmic coat found on clathrin-coated vesicles. Here, we report the molecular and functional characterization of Dictyostelium clathrin-associated AP-1 complex, which in mammalian cells, participates mainly in budding of clathrin-coated vesicles from the trans-Golgi network (TGN). The gamma-adaptin AP-1 subunit was cloned and shown to belong to a Golgi-localized 300-kDa protein complex. Time-lapse analysis of cells expressing gamma-a ...[more]