Ontology highlight
ABSTRACT:
SUBMITTER: Danielli A
PROVIDER: S-EPMC16512 | biostudies-literature | 2000 Jun
REPOSITORIES: biostudies-literature
Danielli A A Loukeris T G TG Lagueux M M Müller H M HM Richman A A Kafatos F C FC
Proceedings of the National Academy of Sciences of the United States of America 20000601 13
Sp22D, a modular serine protease encompassing chitin binding, low density lipoprotein receptor, and scavenger receptor cysteine-rich domains, was identified by molecular cloning in the malaria vector, Anopheles gambiae. It is expressed in multiple body parts and during much of development, most intensely in hemocytes. The protein appears to be posttranslationally modified. Its integral, putatively glycosylated form is secreted in the hemolymph, whereas a smaller form potentially generated by pro ...[more]