Ontology highlight
ABSTRACT:
SUBMITTER: Ramirez JL
PROVIDER: S-EPMC3901800 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Ramirez Jose Luis JL Garver Lindsey S LS Brayner Fábio André FA Alves Luiz Carlos LC Rodrigues Janneth J Molina-Cruz Alvaro A Barillas-Mury Carolina C
Journal of innate immunity 20130724 2
Hemocytes synthesize key components of the mosquito complement-like system, but their role in the activation of antiplasmodial responses has not been established. The effect of activating Toll signaling in hemocytes on Plasmodium survival was investigated by transferring hemocytes or cell-free hemolymph from donor mosquitoes in which the suppressor cactus was silenced. These transfers greatly enhanced antiplasmodial immunity, indicating that hemocytes are active players in the activation of the ...[more]