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Structural and evolutionary analysis of an orangutan foamy virus.


ABSTRACT: The full-length proviral genome of a foamy virus infecting a Bornean orangutan was amplified, and its sequence was analyzed. Although the genome showed a clear resemblance to other published foamy virus genomes from apes and monkeys, phylogenetic analysis revealed that simian foamy virus SFVora was evolutionarily equidistant from foamy viruses from other hominoids and from those from Old World monkeys. This finding suggests an independent evolution within its host over a long period of time.

SUBMITTER: Verschoor EJ 

PROVIDER: S-EPMC165240 | biostudies-literature | 2003 Aug

REPOSITORIES: biostudies-literature

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Structural and evolutionary analysis of an orangutan foamy virus.

Verschoor Ernst J EJ   Langenhuijzen Susan S   van den Engel Saskia S   Niphuis Henk H   Warren Kristin S KS   Heeney Jonathan L JL  

Journal of virology 20030801 15


The full-length proviral genome of a foamy virus infecting a Bornean orangutan was amplified, and its sequence was analyzed. Although the genome showed a clear resemblance to other published foamy virus genomes from apes and monkeys, phylogenetic analysis revealed that simian foamy virus SFVora was evolutionarily equidistant from foamy viruses from other hominoids and from those from Old World monkeys. This finding suggests an independent evolution within its host over a long period of time. ...[more]

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