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Cell surface antigens of Mycoplasma species bovine group 7 bind to and activate plasminogen.


ABSTRACT: Mycoplasma species bovine group 7 bound plasminogen at the cell surface in a lysine-dependent manner. Cell-bound plasminogen was rapidly activated to plasmin by exogenous urokinase, and this activity was associated with plasminogen binding capacity. Binding assays using plasminogen modified with a trifunctional cross-linking agent revealed several binding proteins.

SUBMITTER: Bower K 

PROVIDER: S-EPMC166029 | biostudies-literature | 2003 Aug

REPOSITORIES: biostudies-literature

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Cell surface antigens of Mycoplasma species bovine group 7 bind to and activate plasminogen.

Bower Kylie K   Djordjevic Steven P SP   Andronicos Nicholas M NM   Ranson Marie M  

Infection and immunity 20030801 8


Mycoplasma species bovine group 7 bound plasminogen at the cell surface in a lysine-dependent manner. Cell-bound plasminogen was rapidly activated to plasmin by exogenous urokinase, and this activity was associated with plasminogen binding capacity. Binding assays using plasminogen modified with a trifunctional cross-linking agent revealed several binding proteins. ...[more]

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