In vivo imaging reveals dendritic targeting of laminated afferents by zebrafish retinal ganglion cells.
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ABSTRACT:
SUBMITTER: Mumm JS
PROVIDER: S-EPMC1716713 | biostudies-literature | 2006 Nov
REPOSITORIES: biostudies-literature
Publications
In vivo imaging reveals dendritic targeting of laminated afferents by zebrafish retinal ganglion cells.
Mumm Jeff S JS Williams Philip R PR Godinho Leanne L Koerber Amy A Pittman Andrew J AJ Roeser Tobias T Chien Chi-Bin CB Baier Herwig H Wong Rachel O L RO
Neuron 20061101 4
Targeting of axons and dendrites to particular synaptic laminae is an important mechanism by which precise patterns of neuronal connectivity are established. Although axons target specific laminae during development, dendritic lamination has been thought to occur largely by pruning of inappropriately placed arbors. We discovered by in vivo time-lapse imaging that retinal ganglion cell (RGC) dendrites in zebrafish show growth patterns implicating dendritic targeting as a mechanism for contacting ...[more]
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