Ontology highlight
ABSTRACT:
SUBMITTER: Nguyen Huu S
PROVIDER: S-EPMC1794298 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Nguyen Huu Sau S Oster Michèle M Uzan Serge S Chareyre Fabrice F Aractingi Sélim S Khosrotehrani Kiarash K
Proceedings of the National Academy of Sciences of the United States of America 20070131 6
Fetal progenitor cells enter the maternal circulation during pregnancy and can persist for decades. We aimed to determine the role of these cells in tissue inflammation during pregnancy. WT female mice were mated to males transgenic for the EGFP (ubiquitous) or the luciferase gene controlled by the VEGF receptor 2 (VEGFR2; V-Luc) promoter. A contact hypersensitivity reaction was triggered during such pregnancies. Fetal cells were tracked by using real-time quantitative amplification of the trans ...[more]