Contribution of invariant residues to the function of Rgg family transcription regulators.
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ABSTRACT:
SUBMITTER: Loughman JA
PROVIDER: S-EPMC1797381 | biostudies-literature | 2007 Jan
REPOSITORIES: biostudies-literature
Publications
Contribution of invariant residues to the function of Rgg family transcription regulators.
Loughman Jennifer A JA Caparon Michael G MG
Journal of bacteriology 20061110 2
The Rgg family of transcription regulators is widely distributed among gram-positive bacteria, yet how these proteins control transcription is poorly understood. Using Streptococcus pyogenes RopB as a model, we demonstrated that residues invariant among Rgg-like regulators are critical for function and obtained evidence for a mechanism involving protein complex formation. ...[more]
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2024-06-26 | MSV000095163 | MassIVE