Ontology highlight
ABSTRACT:
SUBMITTER: Wacher C
PROVIDER: S-EPMC1797448 | biostudies-literature | 2007 Jan
REPOSITORIES: biostudies-literature
Wacher Christie C Müller Marcus M Hofer Markus J MJ Getts Daniel R DR Zabaras Regina R Ousman Shalina S SS Terenzi Fulvia F Sen Ganes C GC King Nicholas J C NJ Campbell Iain L IL
Journal of virology 20061101 2
The interferon (IFN)-stimulated genes (ISGs) ISG-49, ISG-54, and ISG-56 are highly responsive to viral infection, yet the regulation and function of these genes in vivo are unknown. We examined the simultaneous regulation of these ISGs in the brains of mice during infection with either lymphocytic choriomeningitis virus (LCMV) or West Nile virus (WNV). Expression of the ISG-49 and ISG-56 genes increased significantly during LCMV infection, being widespread and localized predominantly to common a ...[more]