Ontology highlight
ABSTRACT:
SUBMITTER: Adachi K
PROVIDER: S-EPMC1820511 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Adachi Kenjiro K Soeta-Saneyoshi Chie C Sagara Hiroshi H Iwakura Yoichiro Y
Molecular and cellular biology 20070122 6
Blastocyst formation during mammalian preimplantation development is a unique developmental process that involves lineage segregation between the inner cell mass and the trophectoderm. To elucidate the molecular mechanisms underlying blastocyst formation, we have functionally screened a subset of preimplantation embryo-associated transcripts by using small interfering RNA (siRNA) and identified Bysl (bystin-like) as an essential gene for this process. The development of embryos injected with Bys ...[more]