Novel Pseudomonas aeruginosa gene that suppresses tolerance to carbapenems.
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ABSTRACT:
SUBMITTER: Taniguchi K
PROVIDER: S-EPMC182604 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
Publications
Novel Pseudomonas aeruginosa gene that suppresses tolerance to carbapenems.
Taniguchi Kazuko K Ono Tsuneko T Murakami Keiji K Viducic Darija D Kayama Sizuo S Hirota Katsuhiko K Nemoto Ken K Miyake Yoichiro Y
Antimicrobial agents and chemotherapy 20030901 9
A biapenem-tolerant mutant of Pseudomonas aeruginosa was isolated by Tn1737KH insertion. The survival of the mutant 3 h after the addition of biapenem was about 1000 times greater than that of the wild type. The mutant was also tolerant to other biapenems, such as imipenem, panipenem, and meropenem. ...[more]
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