Ontology highlight
ABSTRACT:
SUBMITTER: Wanyiri JW
PROVIDER: S-EPMC1828422 | biostudies-literature | 2007 Jan
REPOSITORIES: biostudies-literature
Infection and immunity 20061016 1
The apicomplexan parasite Cryptosporidium causes diarrheal disease worldwide. Proteolytic processing of proteins plays a significant role in host cell invasion by apicomplexan parasites. In previous studies, we described gp40/15, a Cryptosporidium sp. glycoprotein that is proteolytically cleaved to yield two surface glycopeptides (gp40 and gp15), which are implicated in mediating infection of host cells. In the present study, we showed that biosynthetically labeled gp40/15 is processed in Crypto ...[more]