Ontology highlight
ABSTRACT:
SUBMITTER: Maeda Y
PROVIDER: S-EPMC1838968 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Maeda Yusuke Y Tashima Yuko Y Houjou Toshiaki T Fujita Morihisa M Yoko-o Takehiko T Jigami Yoshifumi Y Taguchi Ryo R Kinoshita Taroh T
Molecular biology of the cell 20070221 4
Whereas most of the cellular phosphatidylinositol (PI) contain unsaturated fatty chains and are excluded from rafts, GPI-anchored proteins (APs) unusually contain two saturated fatty chains in their PI moiety, and they are typically found within lipid rafts. However, the origin of the saturated chains and whether they are essential for raft association are unclear. Here, we report that GPI-APs, with two saturated fatty chains, are generated from those bearing an unsaturated chain by fatty acid r ...[more]